SCIEX 5500+ LC-MS/MS System
QTRAP®Ready

Quantitative Performance
by Design

Introducing the SCIEX Triple Quad 5500+ System

Built for Quantitative Performance

The SCIEX Triple Quad 5500+ LC-MS/MS System – QTRAP Ready continues the SCIEX legacy of groundbreaking innovations for quantitative performance

Pharma & Biopharma

Food & Beverage Testing

Environmental Testing

Life Science & Clinical Research

Engineered for Enhanced Quantitative Performance

Patented Curtain Gas TM Interface

Proven protection against mass spec contamination providing consistent data quality over long runs with minimal downtime.

Patented Dual QJet ® Ion Guide

Improved ion sampling, collisional focusing and ion transmission for outstanding sensitivity.

Patented Linear Accelerator TM Trap

Activation of QTRAP® functionality offers extra linear ion trap functionality delivering advanced MS 3 qualitative results and unprecedented selectivity for the most challenging analytical assays.

High Energy Dynode (HED) Detector

Extended dynamic range up to 6 orders of magnitude and fast polarity switching of 5 msec for an increased sample throughput.

Patented Q0 High Pressure Cell

High pressure collisional focusing technology enhancing ion transmission for improved sensitivity.

Patented Curtain Gas TM Interface

For fast, true collision-induced fragmentation generating reliable, information-rich, library-searchable MS/MS spectra time after time. Ideal for UHPLC and high throughput analyses with hundreds of compounds.

Behind Every Exceptional Mass Spec

is an Exceptional Ion Source

Rugged, reliable, easily interchangeable ion sources are available for a wide range of applications and flow rates to suit your analysis needs. Rapid source change-over extends system flexibility with minimum downtime. All temperature, gas, and electrical connections are fully integrated into the source housing—no extra lines to attach and no lost time. The system automatically detects and identifies the source without having to make hardware profile changes.

Turbo V™ Ion Source – Robustness and Flexibility for all Your Analytical Workflows

Extraordinary robustness in performance

The simplistic source architecture and orthogonal spray design provides uniform temperature distribution and optimized curtain gas flow to improve robustness and ruggedness

Versatile flow ranges

Covering flow ranges of 5 μL/min to 3 mL/min

Simple plug and play ion source design

A tool-free source design enables plug and play capability with almost zero maintenance

wide compound class coverage

The ability to quickly interchange ionization modes between APCI and ESI enables wider compound class coverage and easy and faster method development

SelexION®Differential Mobility Separation

Extra Selectivity to Overcome Challenging Ion Separations

SelexION technology delivers highly-selective, robust and reproducible ion separation that significantly enhances your quantitative and qualitative performance.

Overcome co-eluting matrix interferences and improve data quality in complex samples
Save time with simplified sample preparation

Reduce background
noise that may be
limiting your LOQ

Separate isobaric
compounds for
increased confidence
in detection

QTRAP®Ready – So Your Lab is Ready Today for the

Analytical Challenges of Tomorrow

The SCIEX Triple Quad 5500+ LC-MS/MS System comes with an upgrade path to QTRAP functionality. Upon quick license activation, the QTRAP Ready functionality will boost your quantification workflows with additional scan types for more data and information out of the same injection.

Multiple Reaction
Monitoring (MRM),
for gold standard
LC-MS/MS quantitation
Enhanced Product
Ion (EPI) for added
confirmation and greater
confidence in your data
Enhanced MS
(EMS) for full
scan workflows
MRM3 provides quantitative
data but also helps remove
interferences from highly
complex matrices for clear
target analyte identification
Enhanced Multiply
Charged (EMC) for an
improved signal-to-noise
of multiply charged ions
Enhanced Resolution (ER)
for greater resolution on
triple quadrupole

Software Integration to Power Your Workflows

Powerful, workflow-driven software ties everything together to deliver a new benchmark in efficiency, throughput, and productivity. Take full advantage of all the power that the SCIEX 5500+ System puts at your fingertips with fully integrated software designed to enhance fast adoption and easy operation.

Analyst® Software

Provides state of the art functionality for instrument control, data analysis and reporting with enhanced performance and ease of use.

SCIEX OS-MQ Software

Advance your data processing capabilities with ease and confidence. SCIEX OS-MQ software is the integrated platform for multiple workflows.

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